Erratum to: Recent advances in capsule-based dry powder inhaler technology

Recent advances in capsule-based dry powder inhaler technology

Pulmonary drug delivery is currently the focus of accelerated research and development because of the potential to produce maximum therapeutic benefit to patients by directly targeting drug to the site of pathology in the lungs. Among the available delivery options, the dry powder inhaler (DPI) is the preferred device for the treatment of an increasingly diverse range of diseases. However, beca...

"Pierce and inhale" design in capsule based dry powder inhalers: Effect of capsule piercing and motion on aerodynamic performance of drugs.

In this work three capsule-based dry powder inhalers, available for generics product development, were compared. Two technologically different dry powder formulations were used in order to relate the capsule piercing position and motion in the device to their aerodynamic performance. A "pierce and inhale" design, in which the capsules pierced with RS01, HandiHaler or Turbospin devices were aero...

Impact of capsule selection on formulation stability in dry powder inhalers (DPIs)

The delivery of inhalation-based formulations is achieved by devices that fall into three segments: nebulizers, metered dose inhalers (MDIs), and dry powder inhalers (DPIs).2 There is much discussion about which device is most appropriate, though that discussion is well beyond the scope of this article. It is of note however, that MDIs and DPIs have been shown to function equally well when pati...

from Capsule - Based Dry Powder Inhalers

Antibacterial loaded Spray Dried Chitosan Polyelectrolyte Complexes as Dry Powder Aerosol for the Treatment of Lung Infections

Inhalation delivery of aerosolized antibacterials is preferred over conventional methods of delivery for targeting lung infection. The present study is concerned with the development and characterization of a novel, spray dried, aerosolized, chitosan polyelectrolyte complex (PEC) based microparticles containing antibacterials for the treatment of lung infections.Chitosan polyelectrolyte complex...